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KMID : 0895420010110030212
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Journal of Korean Society of Occupational and Enviromental Hygiene
2001 Volume.11 No. 3 p.212 ~ p.218
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Environmental and biological monitoring of workers exposed to methyl bromide through quarantine fumigation
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이종성/Lee, Jong-Seong
이용학/신재훈/최정근/오차재/정호근/Lee, Yong-Hag/Shin, Jae-Hoon/Choi, Jung-Keun/O, Cha-Jae/Jung, Ho-Keun
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Abstract
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This study was performed to estimate environmental and biological monitoring of worker exposed to methyl bromide through quarantine fumigation. Airborne methyl bromide and it´s metabolites were analyzed by gas chromatography and ion chromatography, respectively. The results are as followings; airborne concentration of methyl bromide(TWA) was 2.08±1.56 ppm(N=8). Dispersion and setting/degas groups were 0.67±0.12 ppm(N=2) and 2.54±1.53ppm(N=6), respectively. Bromide ion concentration in serum was 23.40±14.91㎎/ℓ(N=10) in the exposed workers and 4.74±0.82㎎/ℓ(N=21) in the non-exposed workers. Bromide ion concentration in urine was 35.56±26.89㎎/ℓ(N=11) in exposed group and 6.62±2.31㎎/ℓ(N=21) in non-exposed group. Good correlation was observed between concentration of serum and urine(r^2=0.890 p<0.01). No significant correlations of other determinanats were observed. Calcuated from a regressive curve. the biological half lifes of serum and urine were 10.7 and 5.9 days.
In these results, biological monitoring of bromide ion of serum and urine provided useful information for evaluating exposure of workers to methyl bromide, so that an availability of bromide ion of biological samples was showed as biological monitoring indices for methyl bromide.
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